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Mattresses With Antimicrobial Fabrics and Materials

Shop antimicrobial mattresses from Serta, Sealy, Beautyrest, Springwall, Evergreen, and iComfort at National Mattress, available in Single/Twin through King sizes across a range of budgets. Each mattress features bacteria-inhibiting fabric technologies like Serta® CoolFeel Fabric™ with Antimicrobial Fibre, Sealy® CleanProtect™, and Beautyrest® Antimicrobial Fibre Technology built directly into the cover and quilt layers. Available in eurotop, tight-top, memory foam, hybrid, and organic latex constructions across extra firm to plush comfort levels. All models are CertiPUR-US® certified, manufactured in Canadian factories, and ship free across Canada with a 365-night sleep trial.

Antimicrobial
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Items

Items

  • Serta Perfect Sleeper 11-inch plush pillow-top, white-blue burst quilting, charcoal sides Serta Perfect Sleeper Premium Mattress Logo
    • 825 Edition Custom Support Coil System
    • CoolFeel Fabric™
    • Gel Band Support
    • Serta® Support Foam
    • PillowSoft® Foam
    • Designed and Made in Canada
    Single/Twin SOLD OUT
    Twin XL SOLD OUT
    Double/Full SOLD OUT
    Queen SOLD OUT
    Compare at $1,499
    King SOLD OUT
    Online availability icon Out Of Stock
    In-Store availability icon On Display:
  • Sealy Posturepedic Plus 1000 Series 11.5-inch firm tight-top mattress, white-blue tufted top, light grey sides Sealy Posturepedic Plus Mattress Logo
    • CleanProtect™ Cover
    • SealyAir™ Fibres
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • SealyResponse™ HD Pocket Coils
    • StableEdge™ HD
    • PROBACK® Quilt with Targeted GelBoost™ HD Memory Foam
    Single/Twin $593
    Twin XL In stock for fast delivery $663
    Double/Full $688
    Queen In stock for fast delivery $746
    Compare at $1,799
    King $988
    Online availability icon In-Stock Only 3 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • SERTA® Classic® 12.5" Medium Euro Top Mattress
    BEST IN CLASS TOP RATED LIMITED STOCK
    Serta Classic 12.5-inch medium euro-top mattress, blue-white ombre plush top, navy floral sides Serta Classic Mattress Logo
    • 800 Edition Custom Support Coil System
    • 3 Zone Body Support + Serta® Support Gel Foam
    • Cool Twist® Gel Memory Foam + Serta® PillowSoft® Foam
    • Serta® Anti-Microbial Fibre Technology
    • Serta® Best Edge® Foam Encasement
    • Designed and Made in Canada
    Single/Twin $657
    Twin XL In stock for fast delivery $703
    Double/Full $713
    Queen $754
    Compare at $1,799
    King $922
    Online availability icon In-Stock Only 3 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • Serta Classic 12.5-inch luxury-plush euro-top mattress, deep blue-white ombre top, navy floral sides Serta Classic Mattress Logo
    • 800 Edition Custom Support Coil System
    • 3 Zone Body Support
    • Cool Twist® Gel Memory Foam + Serta® PillowSoft® Gel Foam
    • Serta® Anti-Microbial Fibre Technology
    • Serta® Best Edge® Foam Encasement
    • Designed and Made in Canada
    Single/Twin $657
    Twin XL In stock for fast delivery $703
    Double/Full $713
    Queen $754
    Compare at $1,799
    King $922
    Online availability icon In-Stock Only 3 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • SERTA® Perfect Sleeper® Celebrate 25th Anniversary 14.5" Firm Super Pillow Top Hybrid Mattress - 1 Serta Perfect Sleeper Premium Mattress Logo
    • 1100 3-Zoned Coil System
    • CoolFeel™ PE Fabric
    • Cool Twist® Gel Memory Foam
    • Serta® Support Gel Foam
    • 10 Year Warranty
    • Made In Canada
    Single/Twin $678
    Twin XL In stock for fast delivery $717
    Double/Full $728
    Queen $776
    Compare at $1,899
    King $937
    Online availability icon In-Stock Only 3 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • SERTA® Perfect Sleeper® Celebrate 25th Anniversary 14.5" Plush Super Pillow Top Hybrid Mattress - 1 Serta Perfect Sleeper Premium Mattress Logo
    • 1100 3-Zoned Coil System
    • CoolFeel™ PE Fabric
    • Cool Twist® Gel Memory Foam
    • Serta® Comfort Gel Foam
    • 10 Year Warranty
    • Made In Canada
    Single/Twin $678
    Twin XL In stock for fast delivery $717
    Double/Full $728
    Queen $776
    Compare at $1,899
    King $937
    Online availability icon In-Stock Only 3 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • Beautyrest 12.5-inch firm tight-top mattress, teal wavy-quilted top with charcoal sides, teal piping and side handles Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • Beautyrest® Firm Gel Support Foam
    • Beautyrest® Support Foam
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $692
    Twin XL In stock for fast delivery $738
    Double/Full $750
    Queen $798
    Compare at $1,899
    King $959
    Online availability icon In-Stock Only 5 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • Sealy Posturepedic Plus 1000 Series 12.5-inch medium-firm euro-top mattress, white-blue tufted top, grey sides Sealy Posturepedic Plus Mattress Logo
    • CleanProtect™ Cover
    • SealyAir™ Fibres
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • SealyResponse™ HD Pocket Coils
    • StableEdge™ HD
    • PROBACK® Quilt with Targeted GelBoost™ HD Memory Foam
    Single/Twin $641
    Twin XL $695
    Double/Full $740
    Queen $807
    Compare at $1,899
    King $1,117
    Online availability icon Backorder Available
    In-Store availability icon On Display:
    Estimated delivery icon Estimated free delivery to M5H 2N1 on Tue, Sep 29
  • Sealy Posturepedic Plus 1000 Series 14-inch plush euro-pillow-top mattress, domed white-blue top, grey sides Sealy Posturepedic Plus Mattress Logo
    • CleanProtect™ Cover
    • SealyAir™ Fibres
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • SealyResponse™ HD Pocket Coils
    • StableEdge™ HD
    • PROBACK® Quilt with Targeted GelBoost™ HD Memory Foam
    Single/Twin $694
    Twin XL In stock for fast delivery $765
    Double/Full $808
    Queen $874
    Compare at $2,099
    King $1,190
    Online availability icon In-Stock Only 2 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • Beautyrest 14-inch medium-firm pillow-top mattress, grey textured cover with charcoal sides, teal piping and side handles Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • Beautyrest® Plush Gel Foam
    • Beautyrest® Support Foam
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $769
    Twin XL In stock for fast delivery $817
    Double/Full $830
    Queen $879
    Compare at $2,099
    King In stock for fast delivery $1,034
    Online availability icon In-Stock Only 6 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • Beautyrest 14-inch firm pillow-top mattress, grey quilted top with teal accents, charcoal sides, blue badge Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • Beautyrest® Medium Gel Foam
    • Beautyrest® Support Foam
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $769
    Twin XL In stock for fast delivery $817
    Double/Full $830
    Queen $879
    Compare at $2,099
    King $1,034
    Online availability icon In-Stock Only 6 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1
  • Beautyrest 12.5-inch extra-firm tight-top mattress, flat grey quilted top with teal waves, charcoal sides Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • SurfaceTouch™ Gel Memory Foam
    • Beautyrest® Extra Firm Gel Foam
    • InfiniCool™ TechnologyBeautyrest®
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $769
    Twin XL In stock for fast delivery $817
    Double/Full $830
    Queen $879
    Compare at $2,099
    King $1,034
    Online availability icon In-Stock Only 1 left!
    In-Store availability icon On Display:
    Free delivery availability icon Free delivery to M5H 2N1 as soon as Tomorrow, Sep 14
    Pickup available icon Only Pickup available to
    M5H 2N1

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How Antimicrobial Mattress Fabrics Work and What to Look For

Antimicrobial mattress fabrics use silver-ion treatments, copper infusions, or engineered fibre technologies to inhibit the growth of odour-causing bacteria and common allergens on the sleep surface. At National Mattress, brands like Serta, Sealy, and Beautyrest each integrate proprietary antimicrobial systems, including Serta® CoolFeel Fabric™ with Antimicrobial Fibre, Sealy® CleanProtect™ Cover Technology, and Beautyrest® Antimicrobial Fibre Technology, directly into the mattress cover and quilt layers for continuous protection that does not wash out over time.

When comparing antimicrobial mattresses, consider what lies beneath the cover as well: hypoallergenic foams certified by CertiPUR-US® ensure the entire mattress, not just the surface, is free of harmful chemicals. Pairing an antimicrobial mattress with a quality mattress protector adds a washable barrier layer for maximum hygiene. All antimicrobial mattresses at National Mattress are manufactured in Canadian factories, ship with free delivery across Canada, and are backed by the manufacturer warranty terms.

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Built-In Antimicrobial Protection

Silver-ion and engineered fibre treatments in the cover and quilt layers actively inhibit bacteria and odour without washing out.

CertiPUR-US® Certified Foams

Every antimicrobial mattress uses independently tested foam free of ozone depleters, heavy metals, formaldehyde, and PBDEs.

❄️

Cooling + Clean Sleep

Most models pair antimicrobial fabrics with cooling technology and breathable covers to manage moisture and temperature.

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Canadian-Made Quality

Manufactured in Canada with free delivery, a 365-night sleep trial, and price-match guarantee.

Frequently Asked Questions About Antimicrobial Mattresses

Do antimicrobial mattress fabrics actually work?
Yes. Technologies like Serta® Antimicrobial Fibre and Sealy® CleanProtect™ are engineered into the fabric at the manufacturing stage to inhibit bacterial growth on the mattress surface. They work continuously and do not diminish with use. Read our detailed breakdown on how antimicrobial fabrics work.
Are antimicrobial mattresses good for allergy sufferers?
Antimicrobial fabrics help reduce bacteria and odour on the sleep surface, but for full allergy protection, look for models also labelled hypoallergenic with CertiPUR-US® certified foams. Pairing with a mattress protector adds a washable dust-mite barrier for the most complete defence.
Which brands at National Mattress offer antimicrobial mattresses?
Six brands carry antimicrobial models: Serta and iComfort (CoolFeel Fabric™ + Antimicrobial Fibre), Sealy (CleanProtect™), Beautyrest (Antimicrobial Fibre Technology), Springwall, and Evergreen. Prices run from budget-friendly to luxury across a wide range of models.
Do I still need a mattress protector with an antimicrobial mattress?
A protector is still recommended. Antimicrobial fabrics inhibit bacteria on the surface, but a mattress protector adds waterproof and dust-mite-proof coverage that keeps your warranty valid and extends the mattress lifespan. See our complete protector guide for options.
What sizes and firmness levels are available in antimicrobial mattresses?
Antimicrobial mattresses at National Mattress are available in Single/Twin, Twin XL, Double/Full, Queen, and King sizes. Firmness options span extra firm, firm, medium, and plush across eurotop, tight-top, memory foam, hybrid, and organic latex constructions.
Do antimicrobial mattresses stop odour and keep the mattress fresh?
Antimicrobial treatments target the bacteria that cause mattress odour, helping the sleep surface stay fresher between cleanings. They are not a substitute for regular care, but they significantly slow bacterial buildup. Learn more in our guide on whether antimicrobial fabrics prevent mattress odour.

Find the Right Antimicrobial Mattress for Your Sleep Style

Our non-commissioned sleep experts can help you compare antimicrobial technologies across brands, no sales pressure, just honest guidance.

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