Medium Mattresses With Antimicrobial Fabrics and Materials

Medium-firmness mattresses — often called medium-firm — sit right between plush and firm, which is why they're the most popular and versatile feel we carry. You get enough cushioning to relieve pressure with enough support to keep your spine aligned, making medium a safe choice for back sleepers, combination sleepers who change positions through the night, and couples who need a compromise between two preferences. Shop medium models from Sealy, Serta, Beautyrest, Stearns & Foster, iComfort and Tempur-Pedic across memory foam, hybrid, euro-top, pillow-top and tight-top builds — with free delivery across Canada. • Feel: medium sits between plush and firm — balanced and the most versatile of our four comfort levels • Also called "medium-firm" — the middle of the firmness scale • Best for: back sleepers, combination sleepers, couples, and most body types • Consider plush if you sleep on your side; firm if you sleep on your stomach or want more support • Constructions: euro-top, tight-top, pillow-top, memory foam and hybrid • Brands: Sealy, Serta, Beautyrest, Stearns & Foster, iComfort, Tempur-Pedic, Springwall & NM • Prices: from $171 to premium

Shop antimicrobial mattresses from Serta, Sealy, Beautyrest, Springwall, Evergreen, and iComfort at National Mattress — 64 models in Single/Twin through King sizes from $179 to $6,640. Each mattress features bacteria-inhibiting fabric technologies like Serta® CoolFeel Fabric™ with Antimicrobial Fibre, Sealy® CleanProtect™, and Beautyrest® Antimicrobial Fibre Technology built directly into the cover and quilt layers. Available in eurotop, tight-top, memory foam, hybrid, and organic latex constructions across extra firm to plush comfort levels. All models are CertiPUR-US® certified, manufactured in Canadian factories, and ship free across Canada with a 365-night sleep trial.

Medium Antimicrobial
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Items

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Medium
  • Sealy Essentials 8-inch medium-firm tight-top foam mattress, quilted blue-grey top, white sides, navy piping Sealy Essentials Mattress Logo
    • CleanProtect™ Fabric
    • SealyLoft™ Quilt with Moisture Wicking Fibres
    • CertiPUR-US™ SealySupport™ HD Foam
    • CertiPUR-US™ SealySupport™ HD Core
    • SealySupport™ HD Foam
    Single/Twin $298
    Twin XL In stock for fast delivery $382
    Double/Full $388
    Queen $420
    Compare at $999
    King $591
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  • SEALY® Essentials 11" Medium Firm Tight Top Mattress
    BEST IN CLASS TOP RATED LIMITED STOCK
    Sealy Essentials 11-inch medium-firm tight-top mattress, blue-speckled flat top, white pinstriped sides Sealy Essentials Mattress Logo
    • CleanProtect™ Fabric
    • SealyLoft™ Quilt with Moisture Wicking Fibres
    • CertiPUR-US™ SealySupport™ HD Foam
    • Posture Touch® Pocket Coils
    • EssentialEdge™ Coil Support
    Single/Twin $409
    Twin XL $423
    Double/Full $462
    Queen $505
    Compare at $1,199
    King $675
    Online availability icon Backorder Available
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    Estimated delivery icon Estimated free delivery to M5H 2N1 on Tue, Aug 25
  • Sealy Essentials 10.5-inch medium-firm euro-top foam mattress, blue-speckled top, white sides on black base Sealy Essentials Mattress Logo
    • CleanProtect™ Fabric
    • SealyLoft™ Quilt with Moisture Wicking Fibres
    • CertiPUR-US™ SealySupport™ HD Foam
    • CertiPUR-US™ SealySupport™ HD Core
    • SealySupport™ HD Foam
    Single/Twin $432
    Twin XL In stock for fast delivery $478
    Double/Full $486
    Queen $505
    Compare at $1,199
    King $655
    Online availability icon In-Stock Only 5 left!
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  • Sealy Posturepedic 800 Series 13-inch medium-firm euro-top mattress, deeply tufted grey-blue top, grey sides Sealy Posturepedic Mattress Logo
    • CleanProtect™ Fabric
    • Quilt Stay True® Quilt with MoistureProtect™ Fibres
    • CertiPUR-US™ SealySupport™ Gel HD Foam
    • Posture Touch® Pocket Coils
    • StableEdge™ HD
    • Targeted Gel HD Foam
    Single/Twin $491
    Twin XL $566
    Double/Full $575
    Queen $642
    Compare at $1,499
    King $904
    Online availability icon Backorder Available
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    Estimated delivery icon Estimated free delivery to M5H 2N1 on Tue, Aug 25
  • SERTA® Classic® 12.5" Medium Euro Top Mattress
    BEST IN CLASS TOP RATED LIMITED STOCK
    Serta Classic 12.5-inch medium euro-top mattress, blue-white ombre plush top, navy floral sides Serta Classic Mattress Logo
    • 800 Edition Custom Support Coil System
    • 3 Zone Body Support + Serta® Support Gel Foam
    • Cool Twist® Gel Memory Foam + Serta® PillowSoft® Foam
    • Serta® Anti-Microbial Fibre Technology
    • Serta® Best Edge® Foam Encasement
    • Designed and Made in Canada
    Single/Twin $657
    Twin XL In stock for fast delivery $703
    Double/Full $713
    Queen $754
    Compare at $1,799
    King $922
    Online availability icon In-Stock Only 3 left!
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  • Sealy Posturepedic Plus 1000 Series 12.5-inch medium-firm euro-top mattress, white-blue tufted top, grey sides Sealy Posturepedic Plus Mattress Logo
    • CleanProtect™ Cover
    • SealyAir™ Fibres
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • SealyResponse™ HD Pocket Coils
    • StableEdge™ HD
    • PROBACK® Quilt with Targeted GelBoost™ HD Memory Foam
    Single/Twin $641
    Twin XL In stock for fast delivery $695
    Double/Full $740
    Queen $807
    Compare at $1,899
    King $1,117
    Online availability icon In-Stock Only 2 left!
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  • Beautyrest 14-inch medium-firm pillow-top mattress, grey textured cover with charcoal sides, teal piping and side handles Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • Beautyrest® Plush Gel Foam
    • Beautyrest® Support Foam
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $769
    Twin XL In stock for fast delivery $817
    Double/Full $830
    Queen $879
    Compare at $2,099
    King $1,034
    Online availability icon In-Stock Only 5 left!
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  • Beautyrest 13-inch medium-firm tight-top mattress, flat grey ribbed quilting with teal accents Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • SurfaceTouch™ Gel Memory Foam
    • Beautyrest® Plush Gel Foam
    • InfiniCool™ Technology
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $769
    Twin XL In stock for fast delivery $817
    Double/Full $830
    Queen In stock for fast delivery $879
    Compare at $2,099
    King $1,034
    Online availability icon In-Stock Only 7 left!
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  • Beautyrest Quintessence 14.5-inch medium firm tight-top mattress, flat grey damask top, herringbone side Beautyrest Quintessence Mattress Collection Logo
    • Beautyrest® T3 Pocketed Coil Technology
    • Beautyrest® Gel Memory Foam
    • WinterCool™ Carbon Foam and GelTouch® Foam
    • WinterCool™ Tri-Fiber with alpaca, cashmere, and silk.
    • WinterCool™ Sleep System with 4 distinct cooling technologies.
    • WinterCool™ Carbon Foam and GelTouch® Foam
    Queen In stock for fast delivery $999
    Compare at $3,499
    King SOLD OUT
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  • Serta Perfect Sleeper Premium 14-inch medium-firm tight-top, blue wave quilting, charcoal sides Serta Perfect Sleeper Premium Mattress Logo
    • 1000 Series 3-Zoned Coil System
    • CoolFeel Fabric™
    • Serta® Antimicrobial Fibre
    • Cool Twist® Gel Memory Foam
    • Serta® Support Foam
    • Designed and Made in Canada
    Twin XL In stock for fast delivery SOLD OUT
    Single/Twin SOLD OUT
    Double/Full SOLD OUT
    Queen SOLD OUT
    Compare at $2,099
    King SOLD OUT
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  • Sealy Posturepedic Plus 1200 Series 15.5-inch medium-firm euro-pillow-top mattress, domed cream top, blue sides Sealy Posturepedic Plus Mattress Logo
    • CleanProtect™ Cover
    • Sealy AirSense™ Fibres Topped with SealyIce™ Yarn
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • Posture Grid® Coil System featuring PostureSense™ Nano Coils
    • SolidEdge™ PRO
    • PROBACK® Plus Quilt with Targeted GelSense™ HD Memory Foam
    Single/Twin $873
    Twin XL In stock for fast delivery $926
    Double/Full $988
    Queen $1,049
    Compare at $2,499
    King $1,279
    Online availability icon In-Stock Only 3 left!
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  • SERTA® Perfect Sleeper® 14.5" Medium Tight Top Mattress - 1 Serta Perfect Sleeper Premium Mattress Logo
    • 1050 3-Zoned Coil System
    • CoolFeel™ Plus Fabric
    • QuiltLoft™ Memory Foam
    • Cool Twist® Gel Memory Foam
    • Serta® Support Foam
    • 10 Year Warranty
    • Made In Canada
    Single/Twin $959
    Twin XL In stock for fast delivery $1,010
    Double/Full $1,026
    Queen $1,078
    Compare at $2,599
    King $1,244
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How Antimicrobial Mattress Fabrics Work and What to Look For

Antimicrobial mattress fabrics use silver-ion treatments, copper infusions, or engineered fibre technologies to inhibit the growth of odour-causing bacteria and common allergens on the sleep surface. At National Mattress, brands like Serta, Sealy, and Beautyrest each integrate proprietary antimicrobial systems — including Serta® CoolFeel Fabric™ with Antimicrobial Fibre, Sealy® CleanProtect™ Cover Technology, and Beautyrest® Antimicrobial Fibre Technology — directly into the mattress cover and quilt layers for continuous protection that does not wash out over time.

When comparing antimicrobial mattresses, consider what lies beneath the cover as well: hypoallergenic foams certified by CertiPUR-US® ensure the entire mattress — not just the surface — is free of harmful chemicals. Pairing an antimicrobial mattress with a quality mattress protector adds a washable barrier layer for maximum hygiene. All antimicrobial mattresses at National Mattress are manufactured in Canadian factories, ship with free delivery across Canada, and include a 10–15 year manufacturer’s warranty.

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Built-In Antimicrobial Protection

Silver-ion and engineered fibre treatments in the cover and quilt layers actively inhibit bacteria and odour without washing out.

CertiPUR-US® Certified Foams

Every antimicrobial mattress uses independently tested foam free of ozone depleters, heavy metals, formaldehyde, and PBDEs.

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Cooling + Clean Sleep

Most models pair antimicrobial fabrics with cooling technology and breathable covers to manage moisture and temperature.

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Canadian-Made Quality

Manufactured in Canada with free delivery, a 365-night sleep trial, and price-match guarantee.

Frequently Asked Questions About Antimicrobial Mattresses

Do antimicrobial mattress fabrics actually work?
Yes. Technologies like Serta® Antimicrobial Fibre and Sealy® CleanProtect™ are engineered into the fabric at the manufacturing stage to inhibit bacterial growth on the mattress surface. They work continuously and do not diminish with use. Read our detailed breakdown on how antimicrobial fabrics work.
Are antimicrobial mattresses good for allergy sufferers?
Antimicrobial fabrics help reduce bacteria and odour on the sleep surface, but for full allergy protection, look for models also labelled hypoallergenic with CertiPUR-US® certified foams. Pairing with a mattress protector adds a washable dust-mite barrier for the most complete defence.
Which brands at National Mattress offer antimicrobial mattresses?
Six brands carry antimicrobial models: Serta and iComfort (CoolFeel Fabric™ + Antimicrobial Fibre), Sealy (CleanProtect™), Beautyrest (Antimicrobial Fibre Technology), Springwall, and Evergreen. Prices range from $179 to $6,640 across 64 models.
Do I still need a mattress protector with an antimicrobial mattress?
A protector is still recommended. Antimicrobial fabrics inhibit bacteria on the surface, but a mattress protector adds waterproof and dust-mite-proof coverage that keeps your warranty valid and extends the mattress lifespan. See our complete protector guide for options.
What sizes and firmness levels are available in antimicrobial mattresses?
Antimicrobial mattresses at National Mattress are available in Single/Twin, Twin XL, Double/Full, Queen, and King sizes. Firmness options span extra firm, firm, medium, and plush across eurotop, tight-top, memory foam, hybrid, and organic latex constructions.
Do antimicrobial mattresses stop odour and keep the mattress fresh?
Antimicrobial treatments target the bacteria that cause mattress odour, helping the sleep surface stay fresher between cleanings. They are not a substitute for regular care, but they significantly slow bacterial buildup. Learn more in our guide on whether antimicrobial fabrics prevent mattress odour.

Find the Right Antimicrobial Mattress for Your Sleep Style

Our non-commissioned sleep experts can help you compare antimicrobial technologies across brands — no sales pressure, just honest guidance.

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