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Plush Medium Mattresses With Antimicrobial Fabrics and Materials

Plush mattresses are the softest comfort level we carry — built with thick pillow-top and euro-top comfort layers (plus plush memory foam and hybrid options) that cradle your shoulders and hips for a soft, sink-in feel. Plush is the top choice for side sleepers and lighter-weight sleepers who need extra cushioning at the pressure points; back and stomach sleepers, or anyone who wants firmer support, may prefer our medium or firm options. Shop plush models from Sealy, Serta, Beautyrest, Stearns & Foster, iComfort and Tempur-Pedic in memory foam, hybrid and pocket-coil builds — with free delivery across Canada. • Feel: plush is the softest of our four comfort levels (plush, medium, firm, extra firm) • Best for: side sleepers and lighter-weight sleepers — cushions shoulders and hips • Consider firmer if: you sleep on your back or stomach, are heavier, or want more support • Plush constructions: pillow-top, euro-top, plush memory foam and hybrid • Builds: memory foam, hybrid and pocket-coil • Brands: Sealy, Serta, Beautyrest, Stearns & Foster, iComfort & Tempur-Pedic • Prices: from $224 to premium
Medium-firmness mattresses — often called medium-firm — sit right between plush and firm, which is why they're the most popular and versatile feel we carry. You get enough cushioning to relieve pressure with enough support to keep your spine aligned, making medium a safe choice for back sleepers, combination sleepers who change positions through the night, and couples who need a compromise between two preferences. Shop medium models from Sealy, Serta, Beautyrest, Stearns & Foster, iComfort and Tempur-Pedic across memory foam, hybrid, euro-top, pillow-top and tight-top builds — with free delivery across Canada. • Feel: medium sits between plush and firm — balanced and the most versatile of our four comfort levels • Also called "medium-firm" — the middle of the firmness scale • Best for: back sleepers, combination sleepers, couples, and most body types • Consider plush if you sleep on your side; firm if you sleep on your stomach or want more support • Constructions: euro-top, tight-top, pillow-top, memory foam and hybrid • Brands: Sealy, Serta, Beautyrest, Stearns & Foster, iComfort, Tempur-Pedic, Springwall & NM • Prices: from $171 to premium

Shop antimicrobial mattresses from Serta, Sealy, Beautyrest, Springwall, Evergreen, and iComfort at National Mattress, available in Single/Twin through King sizes across a range of budgets. Each mattress features bacteria-inhibiting fabric technologies like Serta® CoolFeel Fabric™ with Antimicrobial Fibre, Sealy® CleanProtect™, and Beautyrest® Antimicrobial Fibre Technology built directly into the cover and quilt layers. Available in eurotop, tight-top, memory foam, hybrid, and organic latex constructions across extra firm to plush comfort levels. All models are CertiPUR-US® certified, manufactured in Canadian factories, and ship free across Canada with a 365-night sleep trial.

Plush Medium Antimicrobial
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  • Beautyrest 14-inch medium-firm pillow-top mattress, grey textured cover with charcoal sides, teal piping and side handles Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • Beautyrest® Plush Gel Foam
    • Beautyrest® Support Foam
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $769
    Twin XL In stock for fast delivery $817
    Double/Full $830
    Queen $879
    Compare at $2,099
    King In stock for fast delivery $1,034
    Online availability icon In-Stock Only 6 left!
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  • Beautyrest 13-inch medium-firm tight-top mattress, flat grey ribbed quilting with teal accents Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • SurfaceTouch™ Gel Memory Foam
    • Beautyrest® Plush Gel Foam
    • InfiniCool™ Technology
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $769
    Twin XL In stock for fast delivery $817
    Double/Full $830
    Queen $879
    Compare at $2,099
    King $1,034
    Online availability icon In-Stock Only 4 left!
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  • Serta Perfect Sleeper 13.5-inch plush pillow-top mattress, white blue-burst top, charcoal-navy sides Serta Perfect Sleeper Premium Mattress Logo
    • 850 Edition Custom Support Zoned Coil System
    • CoolFeel Fabric™
    • Serta® Antimicrobial Fibre
    • Cool Twist® Gel Memory Foam
    • Serta® Support Foam
    • Designed and Made in Canada
    Single/Twin SOLD OUT
    Twin XL In stock for fast delivery $392
    Double/Full SOLD OUT
    Queen SOLD OUT
    Compare at $1,999
    King SOLD OUT
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  • SERTA® Perfect Sleeper® 14" Plush Euro Top Mattress - 1 Serta Perfect Sleeper Premium Mattress Logo
    • 950 3-Zoned Coil System
    • CoolFeel™ Fabric
    • PillowSoft® Foam
    • Cool Twist® Gel Memory Foam
    • 10 Year Warranty
    • Made In Canada
    Single/Twin $896
    Twin XL In stock for fast delivery $946
    Double/Full $960
    Queen In stock for fast delivery $1,004
    Compare at $2,399
    King $1,169
    Online availability icon In-Stock Only 4 left!
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  • Serta Perfect Sleeper 14-inch plush hybrid, flat blue floral top, charcoal sides, navy piping Serta Perfect Sleeper Premium Mattress Logo
    • 1000 Series 3-Zoned Coil System
    • CoolFeel Fabric™
    • Serta® PillowSoft® Foam
    • Cool Twist® Gel Memory Foam
    • Hybrid Design
    • Designed and Made in Canada
    Single/Twin SOLD OUT
    Twin XL In stock for fast delivery $471
    Double/Full SOLD OUT
    Queen SOLD OUT
    Compare at $2,099
    King SOLD OUT
    Online availability icon In-Stock Only 5 left!
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  • Serta Perfect Sleeper Premium 14-inch medium-firm tight-top, blue wave quilting, charcoal sides Serta Perfect Sleeper Premium Mattress Logo
    • 1000 Series 3-Zoned Coil System
    • CoolFeel Fabric™
    • Serta® Antimicrobial Fibre
    • Cool Twist® Gel Memory Foam
    • Serta® Support Foam
    • Designed and Made in Canada
    Single/Twin SOLD OUT
    Twin XL SOLD OUT
    Double/Full SOLD OUT
    Queen SOLD OUT
    Compare at $2,099
    King SOLD OUT
    Online availability icon Out Of Stock
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  • Beautyrest 15-inch plush pillow-top mattress, grey ribbed top with teal wave accents, charcoal sides, teal piping and handles Beautyrest Mattress Collection Logo
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • SurfaceTouch™ Gel Memory Foam
    • Beautyrest® Plush Gel Foam
    • InfiniCool™ Technology
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $917
    Twin XL In stock for fast delivery $974
    Double/Full $989
    Queen In stock for fast delivery $1,034
    Compare at $2,499
    King $1,199
    Online availability icon In-Stock Only 5 left!
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  • Sealy Posturepedic Plus 1200 Series 15.5-inch medium-firm euro-pillow-top mattress, domed cream top, blue sides Sealy Posturepedic Plus Mattress Logo
    • CleanProtect™ Cover
    • Sealy AirSense™ Fibres Topped with SealyIce™ Yarn
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • Posture Grid® Coil System featuring PostureSense™ Nano Coils
    • SolidEdge™ PRO
    • PROBACK® Plus Quilt with Targeted GelSense™ HD Memory Foam
    Single/Twin $873
    Twin XL In stock for fast delivery $926
    Double/Full $988
    Queen $1,049
    Compare at $2,499
    King $1,279
    Online availability icon In-Stock Only 3 left!
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  • SERTA® Perfect Sleeper® 14.5" Medium Tight Top Mattress - 1 Serta Perfect Sleeper Premium Mattress Logo
    • 1050 3-Zoned Coil System
    • CoolFeel™ Plus Fabric
    • QuiltLoft™ Memory Foam
    • Cool Twist® Gel Memory Foam
    • Serta® Support Foam
    • 10 Year Warranty
    • Made In Canada
    Single/Twin $959
    Twin XL In stock for fast delivery $1,010
    Double/Full $1,026
    Queen $1,078
    Compare at $2,599
    King $1,244
    Online availability icon In-Stock Only 2 left!
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  • SERTA Perfect Sleeper 13" Plush Smooth Top Mattress, cream marbled top with navy ring-pattern border, corner angle Serta Perfect Sleeper Premium Mattress Logo
    • 1050 3-Zoned Coil System
    • CoolFeel™ Plus Fabric
    • Cool Twist® Gel Memory Foam
    • PillowSoft® Foam
    • Touch-of-Wool TempFibre
    • 10 Year Warranty
    • Made In Canada
    Single/Twin $959
    Twin XL In stock for fast delivery $1,010
    Double/Full $1,026
    Queen In stock for fast delivery $1,078
    Compare at $2,599
    King $1,244
    Online availability icon In-Stock Only 4 left!
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  • Serta Perfect Sleeper Premium 15-inch plush pillow-top, deep-blue floral quilting, charcoal sides Serta Perfect Sleeper Premium Mattress Logo
    • 1000 Series 3-Zoned Coil System
    • CoolFeel Fabric™
    • Serta® Antimicrobial Fibre
    • Cool Twist® Gel Memory Foam
    • Serta® PillowSoft® Foam
    • Designed and Made in Canada
    Single/Twin SOLD OUT
    Twin XL In stock for fast delivery $455
    Double/Full SOLD OUT
    Queen SOLD OUT
    Compare at $2,299
    King SOLD OUT
    Online availability icon In-Stock Only 2 left!
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  • SERTA Perfect Sleeper 15.5" Plush Euro Top Mattress, white marbled euro-top on a navy patterned border Serta Perfect Sleeper Premium Mattress Logo
    • 1050 3-Zoned Coil System
    • CoolFeel™ Plus Fabric
    • QuiltLoft™ Memory Foam
    • Cool Twist® Gel Memory Foam
    • PillowSoft® Foam
    • 10 Year Warranty
    • Made In Canada
    Single/Twin $1,037
    Twin XL In stock for fast delivery $1,089
    Double/Full $1,106
    Queen $1,159
    Compare at $2,799
    King $1,326
    Online availability icon In-Stock Only 3 left!
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How Antimicrobial Mattress Fabrics Work and What to Look For

Antimicrobial mattress fabrics use silver-ion treatments, copper infusions, or engineered fibre technologies to inhibit the growth of odour-causing bacteria and common allergens on the sleep surface. At National Mattress, brands like Serta, Sealy, and Beautyrest each integrate proprietary antimicrobial systems, including Serta® CoolFeel Fabric™ with Antimicrobial Fibre, Sealy® CleanProtect™ Cover Technology, and Beautyrest® Antimicrobial Fibre Technology, directly into the mattress cover and quilt layers for continuous protection that does not wash out over time.

When comparing antimicrobial mattresses, consider what lies beneath the cover as well: hypoallergenic foams certified by CertiPUR-US® ensure the entire mattress, not just the surface, is free of harmful chemicals. Pairing an antimicrobial mattress with a quality mattress protector adds a washable barrier layer for maximum hygiene. All antimicrobial mattresses at National Mattress are manufactured in Canadian factories, ship with free delivery across Canada, and are backed by the manufacturer warranty terms.

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Built-In Antimicrobial Protection

Silver-ion and engineered fibre treatments in the cover and quilt layers actively inhibit bacteria and odour without washing out.

CertiPUR-US® Certified Foams

Every antimicrobial mattress uses independently tested foam free of ozone depleters, heavy metals, formaldehyde, and PBDEs.

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Cooling + Clean Sleep

Most models pair antimicrobial fabrics with cooling technology and breathable covers to manage moisture and temperature.

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Canadian-Made Quality

Manufactured in Canada with free delivery, a 365-night sleep trial, and price-match guarantee.

Frequently Asked Questions About Antimicrobial Mattresses

Do antimicrobial mattress fabrics actually work?
Yes. Technologies like Serta® Antimicrobial Fibre and Sealy® CleanProtect™ are engineered into the fabric at the manufacturing stage to inhibit bacterial growth on the mattress surface. They work continuously and do not diminish with use. Read our detailed breakdown on how antimicrobial fabrics work.
Are antimicrobial mattresses good for allergy sufferers?
Antimicrobial fabrics help reduce bacteria and odour on the sleep surface, but for full allergy protection, look for models also labelled hypoallergenic with CertiPUR-US® certified foams. Pairing with a mattress protector adds a washable dust-mite barrier for the most complete defence.
Which brands at National Mattress offer antimicrobial mattresses?
Six brands carry antimicrobial models: Serta and iComfort (CoolFeel Fabric™ + Antimicrobial Fibre), Sealy (CleanProtect™), Beautyrest (Antimicrobial Fibre Technology), Springwall, and Evergreen. Prices run from budget-friendly to luxury across a wide range of models.
Do I still need a mattress protector with an antimicrobial mattress?
A protector is still recommended. Antimicrobial fabrics inhibit bacteria on the surface, but a mattress protector adds waterproof and dust-mite-proof coverage that keeps your warranty valid and extends the mattress lifespan. See our complete protector guide for options.
What sizes and firmness levels are available in antimicrobial mattresses?
Antimicrobial mattresses at National Mattress are available in Single/Twin, Twin XL, Double/Full, Queen, and King sizes. Firmness options span extra firm, firm, medium, and plush across eurotop, tight-top, memory foam, hybrid, and organic latex constructions.
Do antimicrobial mattresses stop odour and keep the mattress fresh?
Antimicrobial treatments target the bacteria that cause mattress odour, helping the sleep surface stay fresher between cleanings. They are not a substitute for regular care, but they significantly slow bacterial buildup. Learn more in our guide on whether antimicrobial fabrics prevent mattress odour.

Find the Right Antimicrobial Mattress for Your Sleep Style

Our non-commissioned sleep experts can help you compare antimicrobial technologies across brands, no sales pressure, just honest guidance.

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