Will this medium Tempur-Align work on an adjustable base?

Yes, it is rated adjustable-base compatible, and all-foam construction makes it a natural fit since there are no coils to resist the bend. The 10-inch TEMPUR comfort and support layers flex cleanly through head and foot positions. You do not add a box spring on top of an adjustable frame; set the mattress directly on the adjustable platform so it articulates and supports correctly.

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