Will it smell when I unbox it, and is it made with safe materials?

A mild, temporary new-mattress smell is normal for any boxed mattress. The NM Hospitality both-sided pillow-top uses CertiPUR-US certified foams and is fiberglass-free, so the foams are made without ozone depleters and tested for low emissions. Any light odour usually clears within a few days; unbox it, let it expand, and air the room out before adding bedding.