Is this mattress compatible with an adjustable base?

Yes, it is rated compatible with an adjustable bed base. The pocketed coils and foam layers flex at the head and foot without damage, so you can raise and recline freely. It also performs on a platform bed, a slat frame with gaps under roughly 3 inches, or a solid foundation. A traditional flexing coil box spring is not required and is not recommended under a coil mattress, as it undercuts even support.