Does the Chirofoam memory foam mattress need a box spring, or can it go on an adjustable base?

No box spring needed, and it is rated compatible with adjustable bases. Memory foam beds need a firm, flat, fully supportive surface, so a platform bed, slats spaced no wider than about 3 inches, or an adjustable base all work; the all-foam core flexes easily for adjustable frames. A traditional box spring has gaps that can let foam sag and may void coverage. Give the 12-inch core solid, even support underneath and it performs as designed.