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Can this medium memory foam mattress go on an adjustable base?

Yes, it is rated adjustable-base compatible, and as an all-foam bed it bends smoothly with the base since there are no coils to fight. The 12-inch dual-layer TEMPUR comfort and support layers articulate cleanly through head and foot positions. Do not add a box spring on an adjustable frame; set the mattress directly on the adjustable platform so it flexes and supports the way it should.

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