Medium Side Sleeper Antimicrobial Fabrics All Mattresses

Medium mattresses balance cushioning and support — soft enough to relieve pressure, firm enough to keep your spine aligned. This medium-firm feel is the most universally comfortable choice, suiting combination sleepers, couples with different preferences, and most back and side sleepers. Compare every medium option below by brand and profile.
Side sleepers need a mattress that cushions the shoulders and hips while keeping the spine aligned — usually a plush to medium feel with strong pressure relief and contouring. The options below help side sleepers avoid shoulder and hip pain. Compare them by brand, feel, and profile.
Mattresses with antimicrobial fabrics use treated covers that inhibit bacteria, mould, and odour-causing microbes for a fresher, more hygienic sleep surface. Compare every antimicrobial option below by brand, type, and feel.

Shop 200+ mattresses from Serta, Beautyrest, Sealy, Tempur-Pedic, Springwall, and Stearns & Foster at National Mattress — available in Single/Twin through King sizes from $99 to $6,640. Choose from innerspring, euro-top, memory foam, hybrid, and latex constructions in four firmness levels from extra firm to plush. Every mattress is manufactured in Canadian factories using CertiPUR-US® certified foams and ships free across Canada with a 365-night sleep trial, price match guarantee, and manufacturer warranty coverage up to 25 years.

Medium Side Sleeper Antimicrobial Fabrics All Mattresses
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  • SEALY® Essentials 8" Medium Firm Tight Top Foam Mattress SEALY® Essentials 8" Medium Firm Tight Top Foam Mattress brand icon
    • CleanProtect™ Fabric
    • SealyLoft™ Quilt with Moisture Wicking Fibres
    • CertiPUR-US™ SealySupport™ HD Foam
    • CertiPUR-US™ SealySupport™ HD Core
    • SealySupport™ HD Foam
    Single/Twin $207
    Double/Full $261
    Queen $299
    Compare at $999
    Twin XL In stock for fast delivery $355
    King $551
    Online availability icon In-Stock Only 1 left!
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  • SEALY® Essentials 11" Medium Firm Tight Top Mattress SEALY® Essentials 11" Medium Firm Tight Top Mattress brand icon
    • CleanProtect™ Fabric
    • SealyLoft™ Quilt with Moisture Wicking Fibres
    • CertiPUR-US™ SealySupport™ HD Foam
    • Posture Touch® Pocket Coils
    • EssentialEdge™ Coil Support
    Single/Twin $382
    Twin XL In stock for fast delivery $395
    Double/Full $431
    Queen In stock for fast delivery $475
    Compare at $1,199
    King $630
    Online availability icon In-Stock Only 6 left!
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  • SEALY® Essentials 10.5" Medium Firm Eurotop Foam Mattress SEALY® Essentials 10.5" Medium Firm Eurotop Foam Mattress brand icon
    • CleanProtect™ Fabric
    • SealyLoft™ Quilt with Moisture Wicking Fibres
    • CertiPUR-US™ SealySupport™ HD Foam
    • CertiPUR-US™ SealySupport™ HD Core
    • SealySupport™ HD Foam
    Single/Twin $403
    Twin XL In stock for fast delivery $446
    Double/Full $453
    Queen In stock for fast delivery $475
    Compare at $1,199
    King $612
    Online availability icon In-Stock Only 8 left!
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  • SEALY® Posturepedic® 800 Series 13" Medium Firm Euro Top Mattress SEALY® Posturepedic® 800 Series 13" Medium Firm Euro Top Mattress brand icon
    • CleanProtect™ Fabric
    • Quilt Stay True® Quilt with MoistureProtect™ Fibres
    • CertiPUR-US™ SealySupport™ Gel HD Foam
    • Posture Touch® Pocket Coils
    • StableEdge™ HD
    • Targeted Gel HD Foam
    Single/Twin $458
    Twin XL In stock for fast delivery $525
    Double/Full In stock for fast delivery $536
    Queen $595
    Compare at $1,499
    King $845
    Online availability icon In-Stock Only 6 left!
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  • SEALY® Posturepedic Plus® 1000 Series 12.5" Medium Firm Euro Top Mattress SEALY® Posturepedic Plus® 1000 Series 12.5" Medium Firm Euro Top Mattress brand icon
    • CleanProtect™ Cover
    • SealyAir™ Fibres
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • SealyResponse™ HD Pocket Coils
    • StableEdge™ HD
    • PROBACK® Quilt with Targeted GelBoost™ HD Memory Foam
    Single/Twin $598
    Twin XL In stock for fast delivery $648
    Double/Full In stock for fast delivery $691
    Queen In stock for fast delivery $747
    Compare at $1,899
    King $1,043
    Online availability icon In-Stock Only 9 left!
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  • SERTA® Classic® 12.5" Medium Euro Top Mattress SERTA® Classic® 12.5" Medium Euro Top Mattress brand icon
    • 800 Edition Custom Support Coil System
    • 3 Zone Body Support + Serta® Support Gel Foam
    • Cool Twist® Gel Memory Foam + Serta® PillowSoft® Foam
    • Serta® Anti-Microbial Fibre Technology
    • Serta® Best Edge® Foam Encasement
    • Designed and Made in Canada
    Single/Twin $600
    Twin XL In stock for fast delivery $645
    Double/Full $655
    Queen In stock for fast delivery $696
    Compare at $1,799
    King $862
    Online availability icon In-Stock Only 8 left!
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  • BEAUTYREST® 14" Euro Top Medium-Firm Mattress BEAUTYREST® 14" Euro Top Medium-Firm Mattress brand icon
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • Beautyrest® Plush Gel Foam
    • Beautyrest® Support Foam
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin $706
    Twin XL In stock for fast delivery $753
    Double/Full $764
    Queen $805
    Compare at $2,099
    King $974
    Online availability icon In-Stock Only 5 left!
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  • BEAUTYREST® 13" Tight Top Medium-Firm Mattress BEAUTYREST® 13" Tight Top Medium-Firm Mattress brand icon
    • 875 Beautyrest® Pocketed Coil Technology
    • Beautyrest® ActiveResponse Memory Foam
    • SurfaceTouch™ Gel Memory Foam
    • Beautyrest® Plush Gel Foam
    • InfiniCool™ Technology
    • Beautyrest® Antimicrobial Fibre Technology
    Single/Twin In stock for fast delivery $706
    Twin XL In stock for fast delivery $753
    Double/Full $764
    Queen $805
    Compare at $2,099
    King $974
    Online availability icon In-Stock Only 5 left!
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  • SEALY® Posturepedic Plus® 1200 Series 15.5" Medium Firm Europillowtop Mattress SEALY® Posturepedic Plus® 1200 Series 15.5" Medium Firm Europillowtop Mattress brand icon
    • CleanProtect™ Cover
    • Sealy AirSense™ Fibres Topped with SealyIce™ Yarn
    • CertiPUR-US™ SealyComfort™ Gel HD Foam
    • Posture Grid® Coil System featuring PostureSense™ Nano Coils
    • SolidEdge™ PRO
    • PROBACK® Plus Quilt with Targeted GelSense™ HD Memory Foam
    Single/Twin In stock for fast delivery $815
    Twin XL In stock for fast delivery $864
    Double/Full $922
    Queen $971
    Compare at $2,499
    King $1,195
    Online availability icon In-Stock Only 2 left!
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  • SERTA® Perfect Sleeper® Premium 14" Medium Firm Tight Top Mattress SERTA® Perfect Sleeper® Premium 14" Medium Firm Tight Top Mattress brand icon
    • 1000 Series 3-Zoned Coil System
    • CoolFeel Fabric™
    • Serta® Antimicrobial Fibre
    • Cool Twist® Gel Memory Foam
    • Serta® Support Foam
    • Designed and Made in Canada
    Single/Twin $910
    Twin XL In stock for fast delivery $960
    Double/Full $975
    Queen $1,026
    Compare at $2,099
    King $1,191
    Online availability icon In-Stock Only 4 left!
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  • BEAUTYREST® Quintessence™ 14.5" Medium Firm Tight Top Mattress BEAUTYREST® Quintessence™ 14.5" Medium Firm Tight Top Mattress brand icon
    • Beautyrest® T3 Pocketed Coil Technology
    • Beautyrest® Gel Memory Foam
    • WinterCool™ Carbon Foam and GelTouch® Foam
    • WinterCool™ Tri-Fiber with alpaca, cashmere, and silk.
    • WinterCool™ Sleep System with 4 distinct cooling technologies.
    • WinterCool™ Carbon Foam and GelTouch® Foam
    Queen In stock for fast delivery $1,665
    Compare at $3,499
    King $2,049
    Online availability icon In-Stock Only 2 left!
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  • BEAUTYREST® Quintessence™ 18" Medium Firm Super Pillow Top Mattress BEAUTYREST® Quintessence™ 18" Medium Firm Super Pillow Top Mattress brand icon
    • Beautyrest® T3 Pocketed Coil Technology
    • Beautyrest® Gel Memory Foam
    • WinterCool™ Carbon Foam and GelTouch® Foam
    • WinterCool™ Tri-Fiber with alpaca, cashmere, and silk.
    • WinterCool™ Sleep System with 4 distinct cooling technologies.
    • WinterCool™ Carbon Foam and GelTouch® Foam
    Queen In stock for fast delivery $1,897
    Compare at $3,899
    Online availability icon In-Stock Only 1 left!
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